What Research Suggests
A 2025 Cochrane review found that stem cell injections may offer small improvements in knee pain and function compared with placebo. Confidence in this evidence was low.
Read the Cochrane review ↗
Physician-led stem cell care
Understand your options, with a medical review shaped around your knee, your history and your priorities.
Request a consultationPatient advisor first Medical review before treatment
Your care journeyUnderstanding the joint
Understanding your options
Knee osteoarthritis involves changes to cartilage and other tissues within the joint. Pain, stiffness and changes in movement can affect everyday activities differently for each person.
What has changed for you?
Share what happens on stairs, on a walk, or when you get up after sitting.
Describe when it starts, how long it lasts and what you have already tried.
Tell the team which activities matter to you and how your knee affects them.
The evidence behind your decision
A considered decision starts with what research can—and cannot—tell you.
A 2025 Cochrane review found that stem cell injections may offer small improvements in knee pain and function compared with placebo. Confidence in this evidence was low.
Read the Cochrane review ↗Effects on disease progression, quality of life and safety remain uncertain. Studies used different cell preparations, so their results do not establish the outcome of a particular clinic’s protocol.
Published April 2025; the review reports evidence searched through September 2023.
Exercise or physical therapy, weight management where appropriate, medicines and, in some cases, surgery may form part of osteoarthritis care. Discuss the options with your treating clinician.
Explore treatment options · NIH ↗Your treatment options
The medical team reviews your history, knee imaging and previous care to assess suitability. A request does not establish candidacy.
If a plan is recommended, discuss the proposed approach, evidence, risks and alternatives. Stem cell care should not be assumed to replace surgery or other established treatment.
Discuss your caseFrom review to your visit
From your first conversation through your return home, the team coordinates the medical review and the practical details around your clinic visit.
An advisor answers your initial questions. The medical team reviews your case, then guides you through your personalized plan if care is appropriate.
Your coordinator organizes the confirmed schedule, private airport pickup and transportation during your stay. Hotels and flights are not included.
Before departure, the team explains the follow-up arrangements for your plan and how to reach the clinic with questions.
Clinical care & patient support
Get to know the physicians, scientists and patient-support team before you travel.
Meet our team
Before you begin
Diagnosis, treatment expectations and your next step.
No. Knee pain alone does not establish the diagnosis. A clinician considers your history, examines the joint and may use imaging or other tests to understand the cause.
X-rays and MRI show different aspects of a joint. Share any existing reports; the medical team determines what further assessment is needed. Do not arrange a new scan solely to complete this enquiry.
The evidence summarized above does not establish that injections reverse structural damage or restore cartilage in your knee. Improvement in symptoms would not, by itself, demonstrate cartilage regrowth.
The Cochrane review found uncertainty about safety. Joint injections carry an infection risk, and risks may differ with the product and procedure. Your proposed plan needs a discussion of both known risks and remaining uncertainties.
Do not change an agreed surgical plan based on this page. Discuss your symptoms, imaging, established options and any proposed regenerative care with your treating specialist.
An advisor contacts you to arrange a conversation. Share your questions and previous care, then learn what is needed for medical review. If a plan is proposed, costs and visit arrangements should be clear before you decide.
Your next step
Discuss knee osteoarthritis, your previous care and the questions that matter to you. Family members are welcome to enquire.
Your contact details are saved when you continue past the first step, so the team can respond if you leave before finishing. Privacy policy (opens in a new tab)↗
Share your contact details and a little about your interests, then choose a time with a patient advisor.
Start my requestContinue to the clinic’s form and calendar on go.cloudcrm.info.
Call +1 (928) 968-8484 for help.